| Title | Giant Cobblestone-like Papillae During Isotretinoin Therapy. | | Author(s) | Rosen E, Raz J, Segev F | | Institution | Department of Ophthalmology, Meir Medical Center, Kfar Saba, Israel. | | Source | Ocul Immunol Inflamm 2009 Sep-Oct; 17(5):312-3. | | Abstract | Purpose: To report a case of giant cobblestone-like papillae that appeared during oral isotretinoin therapy.
Design: Case report.
Methods: A 14-year-old boy presented with bilateral eye itching for 1 week. Bilateral upper palpebral conjunctival cobblestone-like papillae, superficial punctate keratitis, and shield ulcer in the left cornea were seen. At the time, he was treated with oral isotretinoin for 6 months.
Results: Following cessation of isotretinoin, the ulcer and SPK healed, and the papillae disappeared completely after an 8-week course.
Conclusion: Giant cobblestone-like papillae and corneal shield ulcer may be considered as a probable isotretinoin-induced ocular adverse event. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19831559 |
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