Munro HM, Felix DE, Nykanen DG
Dexmedetomidine/ketamine for diagnostic cardiac catheterization in a child with idiopathic pulmonary hypertension. [Journal Article]
J Clin Anesth 2009 Sep; 21(6):435-8.
The use of a combination of dexmedetomidine and ketamine to provide procedural sedation in a 12-year old boy with a diagnosis of idopathic pulmonary hypertension and a behavioral disorder, undergoing diagnostic cardiac catheterization, is presented. Following a loading dose of ketamine one mg/kg and dexmedetomidine one mcg/kg, an infusion of dexmedetomidine at one mcg/kg/hr was used with the patient breathing spontaneously. Stable hemodynamics were observed throughout the procedure and pulmonary vascular resistance was measured under three conditions. The dexmedetomidine infusion was continued for two hours post-catheterization, facilitating a smooth emergence.
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