| Title | Genetic and molecular insights into the development and evolution of sexual dimorphism. | | Author(s) | Williams TM, Carroll SB | | Institution | Department of Biology, University of Dayton, 300 College Park, Dayton, Ohio 45469, USA. | | Source | Nat Rev Genet 2009 Nov; 10(11):797-804. | | Abstract | Sexual dimorphism is common throughout the animal kingdom. However, a molecular understanding of how sex-specific traits develop and evolve has been elusive. Recently, substantial progress has been made in elucidating how diverse sex-determination systems are integrated into developmental gene networks. One common theme from these studies is that sex-limited traits and gene expression are produced by the combined action of transcriptional effectors of sex-determination pathways and other transcription factors on target gene cis-regulatory elements. Sex-specific traits evolve by the gain, loss or modification of linkages in the genetic networks regulated by sex-determination transcription factors. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19834484 |
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