Does the negative node count affect disease-free survival in early-stage oral cavity cancer? Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons [J Oral Maxillofac Surg] Journal article

Title	Does the negative node count affect disease-free survival in early-stage oral cavity cancer?
Author(s)	Ampil FL, Caldito G, Ghali GE, Baluna RG
Institution	Division of Therapeutic Radiology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA. fampil@lsuhsc.edu
Source	J Oral Maxillofac Surg 2009 Nov; 67(11):2473-5.
MeSH	Adult Aged Aged, 80 and over Carcinoma, Squamous Cell Chi-Square Distribution Cohort Studies Disease-Free Survival Female Follow-Up Studies Head and Neck Neoplasms Humans Kaplan-Meiers Estimate Lymph Nodes Lymphatic Metastasis Male Middle Aged Mouth Neoplasms Neoplasm Staging Predictive Value of Tests Prognosis Retrospective Studies Sentinel Lymph Node Biopsy Severity of Illness Index Survival Rate
Abstract	PURPOSE: We performed a retrospective study to determine whether there is a relationship between disease-free survival and negative lymph node count in patients with resected early-stage oral cavity cancers. MATERIALS AND METHODS: Of the 526 individuals diagnosed with carcinoma of the oral cavity between 1998 and 2005, 52 had undergone primary tumor resection and lymph node dissection of the neck for stage I or II disease. With a mean count of 27 examined negative nodes, these 52 patients were separated into groups with fewer than 27 or > or = 27 uninvolved lymph nodes and compared for disease-free survival. RESULTS: The tumor recurred or progressed in 10 patients (19%) during a median follow-up of 27 months. The 2-year disease-free survival rates were 75% and 78% in individuals with fewer than 27 and > or = 27 uninvolved node counts, respectively (P > .78). CONCLUSION: The removal of a greater number of regional, uninvolved cervical lymph nodes does not correlate with disease-free survival in this particular cohort of patients.
Language	eng
Pub Type(s)	Journal Article
PubMed ID	19837320

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