Resolving response, decision, and strategic control: evidence for a functional topography in dorsomedial prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] Journal article

Title	Resolving response, decision, and strategic control: evidence for a functional topography in dorsomedial prefrontal cortex.
Author(s)	Venkatraman V, Rosati AG, Taren AA, Huettel SA
Institution	Brain Imaging and Analysis Center, Durham, North Carolina 27710, USA.
Source	J Neurosci 2009 Oct 21; 29(42):13158-64.
MeSH	Brain Mapping Cognition Decision Making Female Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Neural Pathways Neuropsychological Tests Oxygen Photic Stimulation Predictive Value of Tests Prefrontal Cortex Problem Solving Reaction Time Regression (Psychology) Young Adult
Abstract	The dorsomedial prefrontal cortex (DMPFC) plays a central role in aspects of cognitive control and decision making. Here, we provide evidence for an anterior-to-posterior topography within the DMPFC using tasks that evoke three distinct forms of control demands--response, decision, and strategic--each of which could be mapped onto independent behavioral data. Specifically, we identify three spatially distinct regions within the DMPFC: a posterior region associated with control demands evoked by multiple incompatible responses, a middle region associated with control demands evoked by the relative desirability of decision options, and an anterior region that predicts control demands related to deviations from an individual's preferred decision-making strategy. These results provide new insight into the functional organization of DMPFC and suggest how recent controversies about its role in complex decision making and response mapping can be reconciled.
Language	eng
Pub Type(s)	Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't
PubMed ID	19846703

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