| Title | Transcription regulation in spermatogenesis. | | Author(s) | Lui WY, Cheng CY | | Institution | School of Biological Sciences, The University of Hong Kong, Pokfulam Road, Hong Kong, China, wylui@hku.hk. | | Source | Adv Exp Med Biol 2009.:115-32. | | Abstract | Spermatogenesis is a highly coordinated process in which diploid spermatogonia (2n) differentiate into mature haploid (1n) spermatozoa in the seminiferous epithelium. In this process, spermatogonia undergo several mitotic divisions and either enter a stem cell renewal pathway, or commit themsevles for further development. Diploid spermatocytes subsequently undergo two meiotic divisions and result in the production of haploid round spermatids. They then enter the process of spermiogenesis in which profound morphological and biochemical restructuring, such as the formation of acrosome and flagellum occur, and give rise to mature spermatozoa. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19856165 |
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