Proteases and their cognate inhibitors of the serine and metalloprotease subclasses, in testicular physiology. Advances in experimental medicine and biology [Adv Exp Med Biol] Journal article | | Title | Proteases and their cognate inhibitors of the serine and metalloprotease subclasses, in testicular physiology. | | Author(s) | Le Magueresse-Battistoni B | | Institution | Inserm U418 and INRA UMR 1245 and Université Lyon 1, Hopital Debrousse, 29 rue soeur Bouvier, 69322, Lyon cedex 05, France, lemagueresse@lyon.inserm.fr. | | Source | Adv Exp Med Biol 2009.:133-53. | | Abstract | The testis is a highly dynamic organ not only in the fetal stage but also during postnatal development and in adult life. It is composed of two major compartments: the interstitium with the steroidogenic Leydig cells, and the seminiferous tubules. The seminiferous tubules are surrounded by peritubular cells. Tubules are composed of Sertoli cells and germ cells at different developmental stages. Sertoli cells play key roles in spermatogenesis. They are target cells for follicle stimulating hormone (FSH) and testosterone, responsible for the initiation and maintenance of spermatogenesis. They form the tubules and provide structural and nutritional support for the developing germ cells1-4. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19856166 |
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