Unbound MEDLINE

Aptamer Fiber Anchored on the Edge of a Protein Pattern: A Template for Nanowire Fabrication. ACS nano [ACS Nano] Journal article

 
TitleAptamer Fiber Anchored on the Edge of a Protein Pattern: A Template for Nanowire Fabrication.
Author(s)Gao P, Cai Y 
InstitutionDepartment of Chemistry, University of Kentucky, 505 Rose Street, Lexington, Kentucky 40506.
SourceACS Nano 2009 Oct 26.
AbstractHow to lay down nanowires at designated positions is a challenge that undermines the development of nanowire-based devices. We demonstrate that aptamer fibers, which are formed by the self-assembly of multiple aptamers, anchor specifically on the edge of protein patterns. This edge-anchoring effect originates from the biospecific recognition between the aptamer and its target protein. The fractal- shaped aptamer fibers are 1-6 nm high and can be tens of micrometers long. Once these edge-bound fibers have formed, they can serve as scaffolds for further assembly processes. We used these aptamer fibers as templates to fabricate palladium and streptavidin nanowires, which anchored on the pattern edges and never cross over or collapse over each other. The aptamer fiber scaffold provides a solution for fabricating and interfacing nanowires to existing surface patterns.
LanguageENG
Pub Type(s)JOURNAL ARTICLE
PubMed ID19856903
  
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