| Title | The Influence of the Recipient's Body Weight on the Probability to Obtain a Heart Transplant-POLKARD HF Registry. | | Author(s) | Zieliński T, Sobieszczańska-Małek M, Browarek A, Piotrowska M, Zakliczyński M, Przybyłowski P, Roguski K, Sadowski J, Zembala M, Korewicki J, POLKARD HF investigators | | Institution | Department of Heart Failure and Transplantation, Institute of Cardiology, Warszawa, Poland. | | Source | Transplant Proc 2009 Oct; 41(8):3166-3170. | | Abstract | INTRODUCTION: The aim of the study was to analyze the influence of body weight of the adult heart recipient on the chance to obtain a transplant.
METHODS: We analyzed the data from all 658 patients listed for heart transplantation.
RESULTS: During the follow-up period, 325 (49%) of listed patients underwent transplantation with 102 (15%) succumbing before heart transplantation. The mean weight of transplanted patients was 73.7 +/- 13.7 kg and 81.2 +/- 15.4 kg for those not transplanted (P < .00001). Patients were divided according to body weight in two groups: light = below 80 kg (n = 360) or heavy >/= 80 kg or above (n = 297). On the transplant list, 111 heavy patients (37%) versus 213 light patients (59%) underwent the procedure, a significant difference. The waiting time among light patients was 255 versus heavy patients of 395 days (P < .005). There was a similar number of deaths before transplantation among the light (n = 56 360 patients; 15.5%) versus the heavy group (49/297; 16%). Upon multivariate Cox mode analysis independent factors related to not receiving a heart transplant were greater weight, systolic blood pressure, pulmonary vascular resistance, Heart Failure Survival Score (HFSS) score and lower N-terminal pro-brain natriuretic peptide (NTproBNP) levels.
CONCLUSIONS: Among adult heart transplant candidates, the chance to receive a heart transplant significantly decreased when the recipient's weight exceeded 80 kg. Patients with a body weight more than 110 kg had a poor chance to receive a heart transplantation. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19857703 |
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