| Title | Experimental study of Love-wave immunosensors based on ZnO/LiTaO(3) structures. | | Author(s) | Zhou FM, Li Z, Fan L, Zhang SY, Shui XJ | | Institution | Lab of Modern Acoustics, Institute of Acoustics, Nanjing University, Nanjing 210093, PR China. | | Source | Ultrasonics 2009 Oct 9. | | Abstract | Experimental study of Love-mode immunosensors based on structures of ZnO/36 degrees YX-LiTaO(3) is presented, in which the ZnO films with c-axis (002) orientation have been successfully grown on the 36 degrees YX-LiTaO(3) substrates by RF magnetron sputtering technique. Then the Love-mode immunosensors based on the ZnO/36 degrees YX-LiTaO(3) structures and monitoring antibody-antigen immunoreactions in aqueous solutions in real time are fabricated. The experimental results show that the optimal thickness of ZnO layers is about 1.20mum in the structures deposited on 36 degrees YX-LiTaO(3) substrates, which is much less than that of SiO(2) overlayers about 6mum. The antibody-antigen immunoreaction experiments also show that the frequency shifts of the sensors with 1.33mum ZnO films are proportional to the concentration of antigen in solution as the concentration range less than 100mug/ml. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19880154 |
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