Krishnamoorthy S, Kekre NS
Detrusor underactivity: To tone or not to tone the bladder? [Journal Article]
Indian J Urol 2009 Jul; 25(3):407-8.
Objectives: The aim of this review was to review the available evidence in literature for the clinical effectiveness of Bethanechol Chloride in patients with detrusor underactivity. Materials&
Methods: We searched all relevant data from Medline and peer-reviewed journals available online on the use of bethanechol in patients with detrusor underactivity.
Results: Most reports that suggest a therapeutic clinical benefit with use of bethanechol have all been anecdotal reports and there is no definite clinical evidence available till date to support its clinical usefulness.
Conclusion: The current available data have shown to offer no definite benefit with the use of parasympathomimetic agents in patients with DU. One of the meta-analysis has shown bethanechol to be ineffective in promoting bladder emptying.
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