| Title | Self-generated theta oscillations in the hippocampus. | | Author(s) | Goutagny R, Jackson J, Williams S | | Institution | [1] Douglas Mental Health University Institute, McGill University, Department of Psychiatry, Montréal, Québec, Canada. [2] These authors contributed equally to this work. | | Source | Nat Neurosci 2009 Nov 1. | | Abstract | Hippocampal theta rhythm is crucial for spatial memory and is thought to be generated by extrinsic inputs. In contrast, using a complete rat hippocampus in vitro, we found several intrinsic, atropine-resistant theta generators in CA1. These oscillators were organized along the septotemporal axis and arose independently from CA3. Our results suggest that CA1 theta rhythm can emerge from the coupling of multiple autonomous hippocampal theta oscillators. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19881503 |
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