Pattern of Disease Onset, Diagnostic Delay, and Clinical Features in Juvenile Onset and Adult Onset Ankylosing Spondylitis. The Journal of rheumatology [J Rheumatol] Journal article | | Title | Pattern of Disease Onset, Diagnostic Delay, and Clinical Features in Juvenile Onset and Adult Onset Ankylosing Spondylitis. | | Author(s) | Ozgocmen S, Ardicoglu O, Kamanli A, Kaya A, Durmus B, Yildirim K, Baysal O, Gur A, Karatay S, Altay Z, Cevik R, Erdal A, Ersoy Y, Sarac AJ, Tekeoglu I, Ugur M, Nas K, Senel K, Ulusoy H | | Institution | From the Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Gevher Nesibe Hospital, Erciyes University, School of Medicine, Kayseri; Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Firat University Hospital, Firat University, Faculty of Medicine, Elazig; Department of Physical Medicine and Rehabilitation, Inonu University, Faculty of Medicine, Malatya; Department of Physical Medicine and Rehabilitation, Ataturk University, Faculty of Medicine, Erzurum; Department of Physical Medicine and Rehabilitation, Dicle University, Faculty of Medicine, Diyarbakir; and Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Yuzuncuyil University, Faculty of Medicine, Van, Turkey. | | Source | J Rheumatol 2009 Nov 2. | | Abstract | OBJECTIVE: To assess the frequency of juvenile onset ankylosing spondylitis (JOAS) in Turkish patients with AS and to compare with adult onset AS (AOAS) in a cross-sectional study design.
METHODS: A total of 322 patients were recruited from the joint database of 5 university hospitals in eastern Turkey.
RESULTS: Patients with JOAS (n = 43, 13.4%) had significantly longer diagnostic delay (9.21 vs 5.08 yrs), less severe axial involvement and more prevalent uveitis (OR 2.92, 95% CI 1.25-6.79), and peripheral involvement at onset (OR 3.25, 95% CI 1.51-6.98, adjusted for current age; and OR 2.26, 95% CI 1.07-4.76, adjusted for disease duration). Patients with AOAS had higher radiographic scores and more restricted clinimetrics but similar functional limitations and quality of life.
CONCLUSION: JOAS and AOAS had distinctive courses and Turkish patients with AS had similar features compared to other Caucasian patient populations. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19884272 |
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