| Title | Itraconazole Treatment of Nonmeningeal Coccidioidomycosis in Children: Two Case Reports and Review of the Literature. | | Author(s) | Homans JD, Spencer L | | Institution | From the Division of Infectious Diseases, Department of Pediatrics, University of Southern California School of Medicine, Los Angeles, CA. | | Source | Pediatr Infect Dis J 2009 Oct 30. | | Abstract | Coccidioides immitis causes a wide range of disease in humans. Fluconazole and itraconazole are effective treatments. Clinical evidence suggests that itraconazole is equivalent or superior to fluconazole in treating osteoarticular infections in rates of cure and recurrence. We report 2 cases of coccidioidomycosis involving bone in children successfully treated with itraconazole oral solution. Itraconazole oral solution is effective in treating nonmeningeal coccidioidomycosis in children, particularly skeletal disease, and infections that are refractory to fluconazole. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19884875 |
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