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Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles. Chemical communications (Cambridge, England) [Chem Commun (Camb)] Journal article

 
Qian ZQ, Zhou F, Du TP, Wang BL, Ding M, Zhao XL, Zhou J 
Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles. [JOURNAL ARTICLE]
Chem Commun (Camb) 2009 Nov 28; (44):6753-6755.


Quinidine derivative (QD)(2)PYR was found to catalyze the asymmetric direct amination of unprotected prochiral 3-oxindole with DIAD to construct quaternary stereocenters at the C3 position with excellent enantioselectivity.



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