Glioblastoma Multiforme in a Patient With Chronic Granulomatous Disease Treated With Subtotal Resection, Radiation, and Thalidomide: Case Report of a Long-term Survivor. Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology [J Pediatr Hematol Oncol] Journal article | | Title | Glioblastoma Multiforme in a Patient With Chronic Granulomatous Disease Treated With Subtotal Resection, Radiation, and Thalidomide: Case Report of a Long-term Survivor. | | Author(s) | Aguilera DG, Tomita T, Rajaram V, Fangusaro J, Katz BZ, Shulman S, Goldman S | | Institution | Divisions of *Hematology-Oncology and Stem Cell transplantation daggerNeurosurgery section signInfectious Diseases double daggerDepartment of Pathology, Children's Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, IL. | | Source | J Pediatr Hematol Oncol 2009 Oct 31. | | Abstract | We report on a child with chronic granulomatous disease who at the age of 13 years was diagnosed with glioblastoma multiforme of the left thalamus. Therapy included subtotal resection, radiation to the tumor bed (60 Gy), and concomitant chemotherapy with daily thalidomide (250 mg/m), both during radiation and for 5 years thereafter. Currently, she is 9 years from diagnosis and has no evidence of disease. Therapy with thalidomide did not increase her infection complications and provided excellent quality of life. This is the first report of glioblastoma multiforme in a patient with chronic granulomatous disease treated with surgery, radiation, and thalidomide who is a long-term survivor. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19887959 |
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