Warnell RL, Swartz CM, Thomson A
Propofol interruption of ECT seizure to reduce side-effects: A pilot study. [JOURNAL ARTICLE]
Psychiatry Res 2009 Nov 3.
Fifteen depressed subjects received six bitemporal electroconvulsive therapy (ECT) treatments under etomidate anesthesia. They were randomized to blindly either receive propofol 0.5mg/kg 15s post-stimulus or not. Propofol infusion significantly prevented long seizures, and prevented cognitive decrements in most neuropsychological tests, several significantly. Propofol interruption may clinically help reduce ECT side-effects.
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