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Methadone-Induced Toxic Leukoencephalopathy: MR Imaging and MR Proton Spectroscopy Findings. AJNR. American journal of neuroradiology [AJNR Am J Neuroradiol] Journal article

 
Salgado RA, Jorens PG, Baar I, Cras P, Hans G, Parizel PM 
Methadone-Induced Toxic Leukoencephalopathy: MR Imaging and MR Proton Spectroscopy Findings. [JOURNAL ARTICLE]
AJNR Am J Neuroradiol 2009 Nov 5.


SUMMARY: We report the clinical, MR imaging, and proton MR spectroscopy findings in a middle-aged woman with proved methadone-induced toxic leukoencephalopathy. The imaging characteristics of this unusual condition have been reported only rarely in the medical literature. We show that the imaging findings in methadone-induced toxic leukoencephalopathy are similar, though not identical, to previously reported cases of neurologic deterioration due to heroin inhalation.



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