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A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum. Fitoterapia [Fitoterapia] Journal article

 
Kong Y, Xiao JJ, Meng SC, Dong XM, Ge YW, Wang RF, Shang MY, Cai SQ 
A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum. [JOURNAL ARTICLE]
Fitoterapia 2009 Nov 9.


Constituents of the fruit of Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus) were investigated. A new flavonoid, 8,2'-diprenylquercetin 3-methyl ether along with 9 known compounds were isolated and identified. Among them, the new compound 8,2'-diprenylquercetin 3-methyl ether exhibited cytotoxic activity against MDA-231 and T47D breast cancer cell lines, quercetin, kaempferol and rutin were isolated from Sinopodophylli Fructus for the first time.



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