Identification and quantitation of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) in human urine by (1)H NMR spectroscopy. Application to five cases of intoxication. Forensic science international [Forensic Sci Int] Journal article | | Title | Identification and quantitation of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) in human urine by (1)H NMR spectroscopy. Application to five cases of intoxication. | | Author(s) | Liu J, Decatur J, Proni G, Champeil E | | Institution | Department of Science, John Jay College of Criminal Justice, City University of New York, 445 west 59th Street, New York, NY, 10019, United States. | | Source | Forensic Sci Int 2009 Nov 16. | | Abstract | Identification of 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) in five cases of intoxication using nuclear magnetic resonance (NMR) spectroscopy of human urine is reported. A new water suppression technique PURGE (Presaturation Utilizing Relaxation Gradients and Echoes) was used. A calibration curve was obtained using spiked samples. The method gave a linear response (correlation coefficient of 0.992) over the range 0.01-1mg/mL. Subsequently, quantitation of the amount of MDMA present in the samples was performed. The benefit and reliability of NMR investigations of human urine for cases of intoxication with MDMA are discussed. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19926414 |
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