| Title | Infectious etiologies of acute febrile illness among patients seeking health care in south-central Cambodia. | | Author(s) | Kasper MR, Blair PJ, Touch S, Sokhal B, Yasuda CY, Williams M, Richards AL, Burgess TH, Wierzba TF, Putnam SD | | Institution | United States Naval Medical Research Unit 2, Jakarta, Indonesia. matthew.kasper@med.navy.mil | | Source | Am J Trop Med Hyg 2012 Feb; 86(2):246-53. | | MeSH | Acute Disease
Adolescent
Adult
Bacteria
Cambodia
Child
Dengue
Developing Countries
Female
Fever
Hantavirus
Hepatitis E virus
Humans
Influenza, Human
Malaria
Male
Orientia tsutsugamushi
Prevalence
Public Health
Rickettsia
Specimen Handling
Young Adult
| | Abstract | The agents of human febrile illness can vary by region and country suggesting that diagnosis, treatment, and control programs need to be based on a methodical evaluation of area-specific etiologies. From December 2006 to December 2009, 9,997 individuals presenting with acute febrile illness at nine health care clinics in south-central Cambodia were enrolled in a study to elucidate the etiologies. Upon enrollment, respiratory specimens, whole blood, and serum were collected. Testing was performed for viral, bacterial, and parasitic pathogens. Etiologies were identified in 38.0% of patients. Influenza was the most frequent pathogen, followed by dengue, malaria, and bacterial pathogens isolated from blood culture. In addition, 3.5% of enrolled patients were infected with more than one pathogen. Our data provide the first systematic assessment of the etiologies of acute febrile illness in south-central Cambodia. Data from syndromic-based surveillance studies can help guide public health responses in developing nations. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.
| | PubMed ID | 22302857 |
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