Growth in young children with chronic renal failure. Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] Journal article | | Title | Growth in young children with chronic renal failure. | | Author(s) | Claris-Appiani A, Bianchi ML, Bini P, Ballabio G, Caraceni MP, Funari C, Terzi F, Romeo L, Rusconi R | | Institution | Istituto di Clinica Pediatrica, Universita' di Milano, Italy. | | Source | Pediatr Nephrol 1989 Jul; 3(3):301-4. | | MeSH | Blood Urea Nitrogen
Bone Development
Child
Child, Preschool
Energy Intake
Female
Growth Disorders
Humans
Hyperparathyroidism
Infant
Kidney Failure, Chronic
Male
| | Abstract | Statural growth and its relation to growth potential, renal function, blood urea nitrogen (BUN), mineral metabolism hormones and dietary intake were studied in 17 prepubertal children (aged 1.6-9.3 years) on conservative treatment for chronic renal failure due to tubulo-interstitial nephropathy. Statural growth (height SDS) was related to the degree of renal failure, was more retarded than ossification, and was independent of the chronological age of the patients. We observed that the lower the glomerular filtration rate (GFR), the lower was the growth potential (increased bone age/statural age ratio). Growth velocity may be normal regardless of statural and bone maturation delay and the degree of renal insufficiency. Impaired growth rate correlated with parathyroid hormone levels, caloric intake and increased blood urea nitrogen during the year of observation. These data show that comprehensive monitoring and suitable treatment must be performed in order to prevent growth retardation at any GFR level. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 2702111 |
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