Unbound MEDLINE

Two doses of MMR vaccine--sufficient to eradicate measles, mumps and rubella? Scandinavian journal of social medicine. [Scand J Soc Med] Journal article

 
TitleTwo doses of MMR vaccine--sufficient to eradicate measles, mumps and rubella?
Author(s)Fahlgren K 
InstitutionDepartment of Social Medicine, Karolinska Institutet, Stockholm, Sweden.
SourceScand J Soc Med 1988; 16(3):129-35.
MeSHAntibodies, Viral
Drug Combinations
Humans
Immunization Schedule
Infant
Measles
Measles Vaccine
Measles-Mumps-Rubella Vaccine
Mumps
Mumps Vaccine
Rubella
Rubella Vaccine
AbstractA review has been done of the available literature on measles, mumps, rubella and vaccines against these diseases. So far, 17 studies on the same virus strains as those in M-M-R II have been published. The rate of seroconversion is practically 100% for rubella, generally more than 90% for measles and between 40 and 100% for mumps. Immediate side effects of vaccination are mild in infants and negligible in schoolchildren. However, the follow-up periods are short. In the only 10-year follow-up published, 14 subjects remained at the end of the period, and the vaccine studied differed from M-M-R II. Large, well-documented studies of MMR vaccination in unselected populations are rare. It must be of crucial importance that the immunity situation is followed up continuously for both vaccinated and non-vaccinated individuals when a mass vaccination programme has been introduced as there will be a risk of outbreaks of diseases mostly among young adults.
Languageeng
Pub Type(s)Journal Article
Review
PubMed ID3057621
  
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