Two doses of MMR vaccine--sufficient to eradicate measles, mumps and rubella? Scandinavian journal of social medicine. [Scand J Soc Med] Journal article | | Title | Two doses of MMR vaccine--sufficient to eradicate measles, mumps and rubella? | | Author(s) | Fahlgren K | | Institution | Department of Social Medicine, Karolinska Institutet, Stockholm, Sweden. | | Source | Scand J Soc Med 1988; 16(3):129-35. | | MeSH | Antibodies, Viral Drug Combinations Humans Immunization Schedule Infant Measles Measles Vaccine Measles-Mumps-Rubella Vaccine Mumps Mumps Vaccine Rubella Rubella Vaccine
| | Abstract | A review has been done of the available literature on measles, mumps, rubella and vaccines against these diseases. So far, 17 studies on the same virus strains as those in M-M-R II have been published. The rate of seroconversion is practically 100% for rubella, generally more than 90% for measles and between 40 and 100% for mumps. Immediate side effects of vaccination are mild in infants and negligible in schoolchildren. However, the follow-up periods are short. In the only 10-year follow-up published, 14 subjects remained at the end of the period, and the vaccine studied differed from M-M-R II. Large, well-documented studies of MMR vaccination in unselected populations are rare. It must be of crucial importance that the immunity situation is followed up continuously for both vaccinated and non-vaccinated individuals when a mass vaccination programme has been introduced as there will be a risk of outbreaks of diseases mostly among young adults. | | Language | eng | | Pub Type(s) | Journal Article Review
| | PubMed ID | 3057621 |
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