| Title | Neurogenic heterotopic ossification. | | Author(s) | Jensen LL, Halar E, Little JW, Brooke MM | | Institution | Department of Physical Medicine and Rehabilitation, Braintree Hospital, Massachusetts 02184. | | Source | Am J Phys Med 1987 Dec; 66(6):351-63. | | MeSH | Animals Bone and Bones Choristoma Diagnosis, Differential Humans Nervous System Diseases Ossification, Heterotopic Soft Tissue Neoplasms
| | Abstract | Neurogenic heterotopic ossification is a potential sequela of neurological disorders, especially spinal cord injury and head injury. The etiology is unknown. Clinical, radiologic, and bone scan findings are typical. Complications may threaten function. The differential diagnosis is crucial in its early stages. Treatment options include diphosphonates, non-steroidal anti-inflammatory drugs, and surgery. This article has reviewed the literature on neurogenic heterotopic ossification (HO), soft tissue ossification of neurologic disease, including pathogenesis, histology, presentation, diagnosis, natural history, complications, and current treatments. | | Language | eng | | Pub Type(s) | Journal Article Review
| | PubMed ID | 3124630 |
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