| Title | Experimental infection in a human subject by a possibly undescribed species of Taenia in Taiwan. | | Author(s) | Chao D, Wong MM, Fan PC | | Institution | Department of Parasitology, National Yang-Ming Medical College, Taipei, Taiwan, Republic of China. | | Source | J Helminthol 1988 Sep; 62(3):235-42. | | MeSH | Adult
Animals
Antibodies, Helminth
Cattle
Chlordiazepoxide
Cysticercosis
Drug Combinations
Enzyme-Linked Immunosorbent Assay
Eosinophilia
Human Experimentation
Humans
Male
Quinacrine
Quinuclidines
| | Abstract | A cysticercus of a possibly undescribed species of Taenia which occurs commonly in Taiwan aborigines was used to establish an experimental infection in a human volunteer. Symptomatic effects attributed to the infection included diarrhoea, upper abdominal pain, and increase or loss of appetite over a four-month period. After an expelled proglottid was observed 122 days post-exposure, eggs and proglottids were found continuously until the patient was treated with anthelmintics. Antibody titres measured by enzyme-linked immunosorbent assay and levels of eosinophilia seemed to correlate with symptoms. Haematological analyses revealed an abnormal lipid metabolism during the entire symptomatic period. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 3192916 |
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