| Title | Mechanism of aortic balloon valvuloplasty: fracture of valvular calcific deposits. | | Author(s) | Isner JM, Samuels DA, Slovenkai GA, Halaburka KR, Hougen TJ, Desnoyers MR, Fields CD, Salem DN | | Institution | Department of Pathology, Tufts University School of Medicine, New England Medical Center, Boston, Massachusetts. | | Source | Ann Intern Med 1988 Mar; 108(3):377-80. | | MeSH | Aged Aged, 80 and over Aortic Valve Stenosis Balloon Dilatation Calcinosis Female Hemodynamic Processes Humans Male Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.
| | Abstract | Balloon valvuloplasty has been shown to acutely reduce the hemodynamic and symptomatic severity of calcific aortic stenosis. The mechanism by which this improvement is accomplished is not known. At necropsy, three patients who died after hemodynamically successful aortic balloon valvuloplasty were found to have aortic valve calcific deposits fractured at one or more sites. These findings suggest that fracture of leaflet calcium represents the basis for successful aortic balloon valvuloplasty. | | Language | eng | | Pub Type(s) | Case Reports Journal Article
| | PubMed ID | 3341674 |
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