Vilkovyskiĭ FA, Zaslavskaia RM, Olevskiĭ IKh, Varshitskiĭ MG, Teĭblium MM [Comparative evaluation of the effect of anaprilin, isoptin and labetalol on the peripheral circulation of hypertension patients] [Journal Article] Farmakol Toksikol 1988 Jan-Feb; 51(1):62-6.
One of the ways of individualization of treating patients with hypertensive disease (HD) is an attempt of an individual action on peripheral blood circulation depending on the initially increased pre- or postloading of the heart. The clinicopharmacological studies showed that the course treatment with low dose anaprilin decreased the pre- and postloading of the heart in HD patients, intravenous administration of isoptin (5 mg) reduced the cardiac preloading and intravenous labetalol (100 mg) decreased the cardiac postloading.
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