| Title | Synthesis of thiadiazol derivatives of 4(3H)-quinazolinone as potential antimicrobial agents. | | Author(s) | Khalil MA, Habib NS | | Institution | Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Egypt. | | Source | Farmaco [Sci] 1987 Dec; 42(12):973-8. | | MeSH | Anti-Bacterial Agents
Anti-Infective Agents
Bacteria
Chemistry
Fungi
Magnetic Resonance Spectroscopy
Microbial Sensitivity Tests
Quinazolines
Spectrophotometry, Infrared
Thiadiazoles
| | Abstract | Three series of quinazolinone derivatives were synthesised namely: 3-[4-(2-substituted amino-1,3,4-thiadiazol-5-yl)phenyl]-2-methyl-4-(3H)- quinazolinones; 3-[4-(2-substituted amino-1,3,4-thiadiazol-5-yl)anilino]-2-methyl-4-(3H)- quinazolinones and 3-[(2-substituted amino-1,3,4-thiadiazol-5-yl)methyl]-2-methyl-4(3H)-quinazolinones. The antimicrobial activity of representative compounds of these series as well as of the starting quinazolinone acids was studied. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 3449395 |
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