| Title | Cranial base changes following surgical treatment of craniosynostosis. | | Author(s) | Marsh JL, Vannier MW | | Source | Cleft Palate J 1986 Dec.:9-18. | | MeSH | Child Cranial Sutures Craniosynostoses Female Follow-Up Studies Humans Infant Infant, Newborn Male Skull Tomography, X-Ray Computed
| | Abstract | Three-dimensional osseous surface images from CT scans have been used to study the endo- and exocranial bases of 87 patients with a variety of craniosynostoses. Patients were studied prior to cranial surgery in infancy, perioperatively, and 1 year postoperatively. The dysmorphology of the endocranial base is diagnostically specific for synostosis of the metopic, sagittal, unicoronal, and bicoronal sutures. Cranio-orbital surgery in infancy for nonsyndromal solitary and bicoronal synostosis seems to induce normalization of endocranial symmetry in the first postoperative year. This normalization occurs to a lesser degree in patients with multiple synostoses. These findings suggest that the cranial base dysmorphology of craniosynostosis is a secondary manifestation of an undefined primary disorder. Furthermore, persistent postoperative dysmorphology may reflect abnormal neural rather than osseous growth. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 3469046 |
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