| Title | Staphylococcus aureus infection as a complication of isotretinoin therapy. |
| Author(s) | Leyden JJ, James WD |
| Source | Arch Dermatol 1987 May; 123(5):606-8. |
| MeSH | Administration, Topical
Anti-Bacterial Agents
Dermatitis
Humans
Isotretinoin
Ointments
Staphylococcal Infections
Staphylococcus aureus
Tretinoin
|
| Abstract | Eighteen patients developed Staphylococcus aureus infection during or shortly after a five-month course of therapy with isotretinoin. Staphylococcus aureus was recovered both from lesions and from the anterior nares. In a prospective study, 4% of control patients treated with isotretinoin alone developed S aureus infection, while none who applied topical antibiotic to the anterior nares developed infection. Control patients had a 64% prevalence of anterior nares colonization with S aureus, compared with 18% in the topical antibiotic group. |
| Language | eng |
| Pub Type(s) | Clinical Trial
Journal Article
Randomized Controlled Trial
|
| PubMed ID | 3472492 |
