| Title | Prolactin-secreting adenoma as part of the multiple endocrine neoplasia--type I (MEN-I) syndrome. |
| Author(s) | Levine JH, Sagel J, Rosebrock G, Gonzalez JJ, Nair R, Rawe S, Powers JM |
| Source | Cancer 1979 Jun; 43(6):2492-6. |
| MeSH | Adenoma
Adult
Amenorrhea
Female
Galactorrhea
Humans
Multiple Endocrine Neoplasia
Neoplasms, Multiple Primary
Pituitary Neoplasms
Pregnancy
Prolactin
Syndrome
|
| Abstract | Two patients presented with the galactorrhea-amenorrhea syndrome. One patient had previously had parathyroid hyperplasia and the other an insulinoma. Preoperative evaluation of each patient revealed hyperprolactinemia and radiological evidence of an abnormal sella turcica. Pituitary adenomas were identified and removed at surgery. Immunostaining techniques confirmed the presence of prolactin-containing cells in both tumors. We propose that prolactin-secreting tumors be considered as part of the MEN-I syndrome, and that patients presenting with the galactorrhea-amenorrhea syndrome be screened and followed sequentially for evidence of other endocrine neoplasia. |
| Language | eng |
| Pub Type(s) | Case Reports
Journal Article
|
| PubMed ID | 36978 |
