| Title | Hyposomatomedinemia in the nursing home patient. | | Author(s) | Rudman D, Nagraj HS, Mattson DE, Erve PR, Rudman IW | | Source | J Am Geriatr Soc 1986 Jun; 34(6):427-30. | | MeSH | Adult
Aged
Aging
Cerebrovascular Disorders
Humans
Insulin-Like Growth Factor I
Male
Middle Aged
Nursing Homes
Somatomedins
| | Abstract | Plasma somatomedin C (SmC) concentration was compared in three groups of men: 58 healthy independent men aged 26 to 45 years; 28 independent men aged 52 to 87 years; and 50 male nursing home residents aged 51 to 95 years. Somatomedin C (mean +/- SE) was 0.73 +/- .04 U/mL, 0.41 +/- .03 U/mL, and 0.33 +/- .03 U/mL in these three groups, respectively (P less than .05 for the differences between all three groups). Somatomedin C less than 0.25 U/mL, a range consistent with severe growth hormone deficiency in children, occurred in 0% of the independent younger men, in 15% of the independent elderly, and in 37% of the nursing home men. Somatomedin C was inversely correlated with age in the independent elderly, but the excess of hyposomatomedinemia in the nursing home men was not explained by age. | | Language | eng | | Pub Type(s) | Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
| | PubMed ID | 3700933 |
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