McVie JG, Simonetti GP, Stevenson D, Briggs RJ, Guelen PJ, de Vos D
The bioavailability of Tamoplex (tamoxifen). Part 1. A pilot study. [Journal Article]
Methods Find Exp Clin Pharmacol 1986 Aug; 8(8):505-12.
Tamoxifen and N-desmethyltamoxifen plasma concentrations were found to be similar after a first single dose and during two months therapy with Tamoplex or Nolvadex in groups of 6 and 8 patients, respectively. Single dose absorption results in 10 healthy male volunteers demonstrated bioequivalence of Tamoplex and Nolvadex 10 mg tablets. A large interindividual variation in tamoxifen absorption data was observed, probably related to the dominating metabolic clearance of tamoxifen.
More from this journalRelated subjects (MeSH) |
