The bioavailability of Tamoplex (tamoxifen). Part 1. A pilot study. Methods and findings in experimental and clinical pharmacology. [Methods Find Exp Clin Pharmacol] Journal article

Title	The bioavailability of Tamoplex (tamoxifen). Part 1. A pilot study.
Author(s)	McVie JG, Simonetti GP, Stevenson D, Briggs RJ, Guelen PJ, de Vos D
Source	Methods Find Exp Clin Pharmacol 1986 Aug; 8(8):505-12.
MeSH	Adult Aged Biological Availability Female Humans Male Middle Aged Pilot Projects Tamoxifen
Abstract	Tamoxifen and N-desmethyltamoxifen plasma concentrations were found to be similar after a first single dose and during two months therapy with Tamoplex or Nolvadex in groups of 6 and 8 patients, respectively. Single dose absorption results in 10 healthy male volunteers demonstrated bioequivalence of Tamoplex and Nolvadex 10 mg tablets. A large interindividual variation in tamoxifen absorption data was observed, probably related to the dominating metabolic clearance of tamoxifen.
Language	eng
Pub Type(s)	Journal Article
PubMed ID	3747644

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