| Title | Abuse of pentazocine-naloxone combination. | | Author(s) | Reed DA, Schnoll SH | | Source | JAMA 1986 Nov 14; 256(18):2562-4. | | MeSH | Adult
Drug Combinations
Drug Interactions
Humans
Injections, Intravenous
Male
Naloxone
Pentazocine
Street Drugs
Substance-Related Disorders
Tripelennamine
| | Abstract | The combination of pentazocine hydrochloride and tripelennamine hydrochloride (T's and blues) has been abused as a heroin substitute. In response to this abuse, the formulation of pentazocine has been changed to include naloxone hydrochloride, a short-acting narcotic antagonist, in the tablet (Talwin Nx). Two cases of abuse of the new pentazocine and naloxone formulation along with tripelennamine are reported. Potential reasons for the failure of naloxone to block the effects of pentazocine are discussed. | | Language | eng | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 3773159 |
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