Nickoloff BJ, Misra P, Morhenn VB, Hintz RL, Rosenfeld RG Plasma somatomedin-C levels in psoriasis. [Journal Article, Research Support, Non-U.S. Gov't , Research Support, U.S. Gov't, P.H.S. ] Br J Dermatol 1987 Jan; 116(1):15-20.
We have measured plasma levels of somatomedin-C, one of the principal mediators of growth hormone action, in 25 patients with plaque-type psoriasis of varying severity and compared these levels with those found in healthy controls. Plasma somatomedin-C levels were not elevated in the psoriatic patients regardless of the severity of their disease, suggesting that in these patients growth hormone secretion is within normal limits.
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