| Title | Auditory brainstem-evoked response after single-dose injection of lidocaine and tocainide. |
| Author(s) | Wästerström SA |
| Source | Scand Audiol 1985; 14(1):41-5. |
| MeSH | Adult
Audiometry, Evoked Response
Auditory Pathways
Brain Stem
Comparative Study
Evoked Potentials, Auditory
Humans
Lidocaine
Reaction Time
Research Support, Non-U.S. Gov't
Tocainide
|
| Abstract | In order to investigate the effects of tocainide and lidocaine on the auditory brainstem-evoked response (ABR), 10 healthy male subjects 20-40 years of age were given a single i.v. dose of 250 mg of tocainide and of 100 mg of lidocaine on separate occasions in a trial with a double-blind cross-over design. Neither drug produced any significant change in absolute or interpeak intervals, or in latency-intensity functions (wave V). The results fail to indicate that lidocaine and tocainide in the doses given influence the synaptic transmission and conduction velocity in the cochlear nerve or in the brainstem. |
| Language | eng |
| Pub Type(s) | Clinical Trial
Controlled Clinical Trial
Journal Article
|
| PubMed ID | 3933102 |
