| Title | Comparative diagnosis of alcoholic liver diseases by multivariate and histological analysis. | | Author(s) | Kitadai M, Itoshima T, Hattori S, Ukida M, Ito T, Ogawa H, Mizutani S, Tanaka R, Kita K, Nagashima H | | Source | Acta Med Okayama 1985 Feb; 39(1):11-8. | | MeSH | Adult
Analysis of Variance
Comparative Study
Diagnosis, Differential
Fatty Liver, Alcoholic
Hepatitis, Alcoholic
Humans
Liver Cirrhosis, Alcoholic
Liver Diseases, Alcoholic
Liver Function Tests
Middle Aged
| | Abstract | Sixty-seven cases of alcoholic liver disease were histologically classified into 4 groups: alcoholic liver cirrhosis (ALC), alcoholic hepatitis (AH), alcoholic liver fibrosis (ALF) and alcoholic fatty liver (AFL). They were statistically reclassified by the likelihood method using age, total alcohol intake, hepatomegaly and 12 liver function tests. A score table for likely diagnosis was constructed from the incidences of each range. The cases were re-evaluated using the score table, with an overall correct diagnosis rate of 73%. The best combination of 5 parameters included the indocyanine green plasma disappearance rate, total alcohol intake, cholesterol, choline esterase and glutamic oxaloacetic transaminase/glutamic pyruvic transaminase ratio. A correct diagnosis rate of 75% was attained using these 5 parameters, and 94% of patients were correctly diagnosed by the first or the second likelihood diagnosis. Differential diagnosis of alcoholic liver diseases was easily and confidently obtained with the likelihood score table. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 3984778 |
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