Harkaway PS, Conlon PF, Hirsh JD, Allen WT Comparison of two sustained-release theophylline preparations in adult patients with obstructive airways disease. [Clinical Trial, Controlled Clinical Trial, Journal Article] J Clin Pharmacol 1985 Sep; 25(6):444-7.
The bioavailability profiles of two sustained-release oral theophylline preparations, Respbid and Theo-Dur, were compared in 19 adults with obstructive airways disease. Intravenous aminophylline was used as the reference standard. No significant differences were detected in fraction absorbed, peak-trough fluctuations, or time to peak concentrations.
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