Syndromes associated with deletion of the long arm of chromosome 18[del(18q)]. American journal of medical genetics. [Am J Med Genet] Journal article

Title	Syndromes associated with deletion of the long arm of chromosome 18[del(18q)].
Author(s)	Wilson MG, Towner JW, Forsman I, Siris E
Source	Am J Med Genet 1979; 3(2):155-74.
MeSH	Abnormalities, Multiple Adolescent Child Child, Preschool Chromosome Banding Chromosome Deletion Chromosomes, Human, 16-18 Chromosomes, Human, 6-12 and X Face Female Growth Disorders Humans Immunoglobulins Infant Karyotyping Male Mental Retardation Research Support, U.S. Gov't, P.H.S. Syndrome Translocation, Genetic
Abstract	We studied eight persons whose karyotypes demonstrated deletion of a portion of the long arm of chromosome 18. Seven of these persons who showed the typical del(18q) syndrome had a common deletion in band 18q21, most likely band q21.3, and in at least two persons the deletion was interstitial. Another mentally retarded child, dissimilar in appearance, had a more proximal deletion within band 18q12. Two different clinical syndromes resulted from deletions of these different segments of the long arm of chromosome 18.
Language	eng
Pub Type(s)	Case Reports Journal Article
PubMed ID	474629

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