Venencie PY, Winkelmann RK, Moore BA Ultrastructural findings in the skin lesions of patients with anetoderma. [Case Reports, Journal Article] Acta Derm Venereol 1984; 64(2):112-20.
Eight biopsy specimens from the skin lesions of five patients with anetoderma were studied for their ultrastructural findings. In all of them, normal elastic fibers were absent and a few very thin, irregular elastic fibers with a more or less complete loss of the amorphous substance and a relative conservation of the microfibrils were observed. The collagen fibers were normal. Inflammation composed of macrophages and lymphocytes, with some plasma cells, was a prominent finding. It is suggested that anetoderma and acquired cutis laxa are part of the same spectrum of elastolytic disease.
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