Primary biliary cirrhosis. A patient with adverse reactions to tiopronin and autoimmune hemolytic anemia with reticulocytopenia. Archives of internal medicine. [Arch Intern Med] Journal article | | Title | Primary biliary cirrhosis. A patient with adverse reactions to tiopronin and autoimmune hemolytic anemia with reticulocytopenia. | | Author(s) | Shichiri M, Koyama W, Tozuka S, Sakamoto S, Kanayama M | | Source | Arch Intern Med 1984 Jan; 144(1):89-91. | | MeSH | Amino Acids, Sulfur
Anemia, Hemolytic, Autoimmune
Bone Marrow
Drug Eruptions
Female
Humans
Hyperplasia
Liver Cirrhosis, Biliary
Methylprednisolone
Middle Aged
Prednisolone
Reticulocytes
Thiopronine
| | Abstract | A 32-year-old woman with asymptomatic primary biliary cirrhosis had autoimmune hemolytic anemia associated with reticulocytopenia and thrombocytopenia despite an intensely erythroid bone marrow. Her anemia was successfully treated with oral prednisolone and intravenous pulse methylprednisolone, with a rapid response of reticulocytosis and sustained erythrocytosis. Tiopronin therapy was later initiated and resulted in fever, rash, exacerbation of the liver disease, and positive direct and indirect antiglobulin tests. | | Language | eng | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 6229229 |
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