Lange G Transtympanic gentamycin in the treatment of Ménière's disease. [Journal Article] Rev Laryngol Otol Rhinol (Bord) 1995; 116(2):151-2.
Severe cases of Ménière's disease are successfully treated with ototoxic antibiotics. Gentamycin sulphate gives the best results. With the aid of a small syringe the drug is introduced into the external auditory canal 3-5 times per day. From there it is transported into the middle ear through a ventilating tube (Grommet) under slight pressure (Politzer bag). The liquid then penetrates the round and oval windows and influences inner-ear function. More than 90% of our patients in 25 years after therapy had no further attacks.
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