| Title | The use of glycolic acid as a peeling agent. | | Author(s) | Murad H, Shamban AT, Premo PS | | Institution | Department of Dermatology, University of California Los Angeles School of Medicine, USA. | | Source | Dermatol Clin 1995 Apr; 13(2):285-307. | | MeSH | Chemexfoliation
Drug Combinations
Face
Glycolates
Humans
Patient Care Planning
Pigmentation Disorders
Research Support, Non-U.S. Gov't
Skin
Skin Aging
Skin Care
| | Abstract | Glycolic acid is a member of the AHA family, which occurs naturally in foods and has been used for centuries as a cutaneous rejuvenation treatment. Recently it has proved to be a versatile peeling agent and it is now widely used to treat many defects of the epidermis and papillary dermis in a variety of strengths, ranging from 20% to 70%, depending on the condition being treated. People of almost any skin type and color are candidates, and almost any area of the body can be peeled. Several weeks prior to a peel the skin may be prepared with topical tretinoin or glycolic acid, and immediately prior to the peel the skin may be degreased with a variety of agents. Following the peel the skin is carefully observed for any complications such as hyperpigmentation and infection. Results are maintained with serial peels and at-home use of tretinoin or glycolic acid, as well as sun avoidance. The glycolic acid can be applied simultaneously with TCA and is another technique for a medium-depth peel. Comparison of 35% TCA-treated skin with 70% glycolic acid-treated skin examined histologically at different times reveals similar changes in papillary dermis connective tissue proteins, epidermal necrosis seen only with TCA, and reversion at 2 years postpeel to pretreatment appearance. | | Language | eng | | Pub Type(s) | Journal Article
Review
| | PubMed ID | 7600706 |
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