Kornely E, Schlaghecke R
Complete remission of metastasized adrenocortical carcinoma under o,p'-DDD. [Case Reports, Journal Article]
Exp Clin Endocrinol 1994; 102(1):50-3.
The case of a 53 year old female patient with metastasized androgen producing adrenocortical carcinoma is presented. After initial adrenalectomy a local relapse had been treated by surgery and external irradiation. Solitary liver metastases had been resected repeatedly. Subsequently multiple liver metastases required systemic chemotherapy. Treatment with o,p'-DDD (initially 12 g/d, long term treatment 1.5-3 g/d) has resulted in a complete remission for nearly 4 years. Gastrointestinal side effects occurred initially but subsided with dose reduction of o,p'-DDD.
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