Complete remission of metastasized adrenocortical carcinoma under o,p'-DDD. Experimental and clinical endocrinology. [Exp Clin Endocrinol] Journal article | | Title | Complete remission of metastasized adrenocortical carcinoma under o,p'-DDD. | | Author(s) | Kornely E, Schlaghecke R | | Institution | Abteilung für Endokrinologie und Rheumatologie, Heinrich Heine Universität, Düsseldorf, Germany. | | Source | Exp Clin Endocrinol 1994; 102(1):50-3. | | MeSH | Adrenal Cortex Neoplasms
Adrenalectomy
Female
Humans
Liver Neoplasms
Middle Aged
Mitotane
Remission Induction
| | Abstract | The case of a 53 year old female patient with metastasized androgen producing adrenocortical carcinoma is presented. After initial adrenalectomy a local relapse had been treated by surgery and external irradiation. Solitary liver metastases had been resected repeatedly. Subsequently multiple liver metastases required systemic chemotherapy. Treatment with o,p'-DDD (initially 12 g/d, long term treatment 1.5-3 g/d) has resulted in a complete remission for nearly 4 years. Gastrointestinal side effects occurred initially but subsided with dose reduction of o,p'-DDD. | | Language | eng | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 8005209 |
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