Unbound MEDLINE

[Transformation of hepatic adenoma into hepatocellular carcinoma in patients with prolonged use of oral contraceptives] Revista do Hospital das Clínicas. [Rev Hosp Clin Fac Med Sao Paulo] Journal article

 
Title[Transformation of hepatic adenoma into hepatocellular carcinoma in patients with prolonged use of oral contraceptives]
Author(s)Herman P, Machado MA, Volpe P, Pugliese V, Vianna MR, Bacchella T, Machado MC, Pinotti HW 
InstitutionDepartamento de Gastroenterologia da Faculdade de Medicina da Universidade de São Paulo.
SourceRev Hosp Clin Fac Med Sao Paulo 1994 Jan-Feb; 49(1):30-3.
MeSHAdenoma, Liver Cell
Adult
Carcinoma, Hepatocellular
Contraceptives, Oral
English Abstract
Female
Humans
Liver Neoplasms
Time Factors
AbstractLiver cell adenomas were relatively rare until the use of oral contraceptives. Most of these tumors have occurred in otherwise healthy young women who have been exposed to oral contraceptives. The treatment of this condition remained controversial for a long time. However, bleeding is still a frequent complication and can lead to a significant mortality rate. The better surgical results in hepatic resection, due to technological advances, has contributed to the indication of surgical management as therapeutic option in hepatic cell adenoma. Some authors believe that liver cell adenomas were potentially premalignant and could degenerate into hepatocellular carcinoma but there is very few well documented reports of this transformation. We report our experience in the management of liver cell adenoma.
Languagepor
Pub Type(s)Case Reports
Journal Article
PubMed ID8029613
  
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