| Title | [Morphologic rationale for selecting composition and structure of biologically active material based on sodium alginate for wound treatment] |
| Author(s) | Gliantsev SP, Annaev AG, Savvina TV |
| Source | Biull Eksp Biol Med 1993 Jan; 115(1):65-7. |
| MeSH | Alginates
Animals
Drug Combinations
Endopeptidases
Glucuronic Acid
Hexuronic Acids
Necrosis
Rats
Sisomicin
Wound Healing
Wound Infection
|
| Abstract | Morphological evaluation of composition and structure of a biologically active compound (BAC) based on sodium alginate, comprising 1% sizomycin and 0.25% protease C, on wound healing in infected rats wounds was made in experiment. The results have clearly shown that for the infected wound treatment during the first period of wound healing BAC of polyfunctional action must be applied. Biologically active substances (sizomycin and protease C) promote removal of inflammatory etiopathogenic factors, i. e. necrotic tissues and microbic bodies, while polysaccharide basis of the composition promotes stimulation of reparative processes in the wounds. Powder with granules size 315 m including 24% potassium gluconate is believed most suitable BAC structure. |
| Language | rus |
| Pub Type(s) | English Abstract
Journal Article
|
| PubMed ID | 8054584 |
