| Title | Changes in auditory evoked responses during intravenous lidocaine. | | Author(s) | Ueda S, Aso S, Watanabe Y, Mizukoshi K | | Institution | Department of Otolaryngology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan. | | Source | Acta Otolaryngol Suppl 1993.:89-93. | | MeSH | Audiometry, Evoked Response
Brain Stem
Cochlear Nerve
Evoked Potentials, Auditory, Brain Stem
Female
Humans
Infusions, Intravenous
Lidocaine
Male
Middle Aged
Reaction Time
Research Support, Non-U.S. Gov't
Tinnitus
| | Abstract | Auditory evoked responses in 21 cases with tinnitus were recorded before and after the administration of intravenous lidocaine. A dosage of 1 mg/kg body weight was diluted with 20% glucose (20 ml) and administered intravenously over a one-min period. The loudness of tinnitus was evaluated during electrocochleography (ECochG) or auditory brain-stem response (ABR) recordings using a score between 0 and 11. The stimulus sound was a tone burst in a frequency that corresponded to the pitch of tinnitus. AP latency on ECochG and the inter peak latency (IPL) of wave I-III and wave III-V on ABR were prolonged momentarily and tinnitus was reduced. These findings reveal that the sites of action for lidocaine are both the inner ear and the brain-stem. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 8470541 |
|
