| Title | Clinical manifestations and management of the antiphospholipid syndrome. | | Author(s) | Derksen RH | | Institution | Department Internal Medicine (F02.126), University Hospital Utrecht. | | Source | Lupus 1996 Apr; 5(2):167-9. | | MeSH | Adrenal Cortex Hormones
Antibodies, Antiphospholipid
Anticoagulants
Antiphospholipid Syndrome
Diagnosis, Differential
Humans
Lupus Erythematosus, Systemic
Plasma Exchange
| | Abstract | Since the original description of associations between lupus anticoagulant and anticardiolipin antibodies with thrombosis, fetal loss and thrombocytopenia, several distinct clinical manifestations related to this so-called antiphospholipid syndrome have appeared in the literature. Retrospective studies indicate that long-term treatment with oral anticoagulants can effectively reduce the chance of recurrent thrombosis. However, data from controlled prospective studies are urgently needed to enable optimal counselling of patients suffering from this syndrome. | | Language | eng | | Pub Type(s) | Journal Article
Review
| | PubMed ID | 8743135 |
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